John O'Donnell (1749–1805) was an Irish merchant based in Baltimore, Maryland. After spending many years in his early life adventuring and trading in the Far East, he settled in Baltimore, establishing a plantation that would become the neighbourhood of Canton.

A bronze statue of him, sculpted by Tylden Streett^[1] stood in Canton's O'Donnell Square Park from 1980^[2] to 2021, when it was ordered removed by Mayor Brandon Scott.^[3]

O'Donnell, born in Limerick, Ireland in 1749,^[2] was a merchant whose ship, the Pallas, is believed to be the first to reach China from Baltimore, Maryland.^[4] His ship returned to the city in August 1785, carrying rich cargo including teas, porcelain, satins, silk, paper wall-hangings, cinnamon, rhubarb, and opium.^[5] Upon hearing of the sale, George Washington sent Colonel Tench Tilghman with a list of articles he wanted "if great bargains are to be had — my purchases depends entirely on the prices".^[4] In 1786, he purchased a 2,000-acre plot in Baltimore using the profits earned from selling the goods, naming it after the Chinese city of Guangzhou (anglicized as Canton) in honor of the goods he brought back from the city.^[3][6] The neighborhood of Canton, Baltimore, along with its O'Donnell Square, would take its name from O'Donnell's property.^[7][8] The 1790 United States census listed 36 enslaved people lived on O'Donnell's plantation.^[3]

O'Donnell later made another voyage to the East, returning after an absence of two and a half years on June 29, 1789, and offering his ship, the Chesapeake, and its cargo from India and China for sale. The Chesapeake was the first American vessel to trade with India and the first to fly the United States flag on the River Ganges. After his return, he asked Secretary of State Thomas Jefferson twice, first in 1789 and again in 1793, to serve as the commissioner of the United States to India. He was turned down both times.^[4]

O'Donnell died at age 56 at Canton on October 5, 1805. At the time of his death, he was one of the wealthiest men in the United States. He was buried at the Westminster Hall and Burying Ground,^[4] but was later reinterred in a family plot at Green Mount Cemetery.^[3]

A bronze statue of O'Donnell, designed by local artist Tylden Streett, was erected in O'Donnell Square Park by the Canton Improvement Association in 1980, two years after the neighborhood was added to the National Register of Historic Places.^[9][10] A marker installed by the administration of Baltimore Mayor William Donald Schaefer called O'Donnell "a man of great vision and accomplishment".^[11]