Jennifer Doudna

Jennifer Anne Doudna ForMemRS (/ˈddnə/;[1] born February 19, 1964)[2] is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing."[3][4] She is the Li Ka Shing Chancellor's Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997.[5]

Jennifer Doudna
Born
Jennifer Anne Doudna

(1964-02-19) February 19, 1964 (age 58)
Washington, D.C., U.S.
EducationPomona College (BA)
Harvard University (MA, PhD)
Known for
SpouseJames Cate
Awards
Scientific career
FieldsBiochemistry
CRISPR
RNA biology
Gene editing
InstitutionsUniversity of Colorado, Boulder
Yale University
University of California, Berkeley
Gladstone Institutes
University of California, San Francisco
ThesisTowards the Design of an RNA Replicase (1989)
Doctoral advisorJack Szostak
Other academic advisorsThomas Cech
Doctoral studentsRachel Haurwitz
Janice Chen
Lei Stanley Qi
WebsiteDoudna Lab website
Hughes Institute website

Doudna graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also president and chair of the board of the Innovative Genomics Institute, a faculty scientist at Lawrence Berkeley National Laboratory, a senior investigator at the Gladstone Institutes, and an adjunct professor of cellular and molecular pharmacology at the University of California, San Francisco (UCSF).[6][7][8][9] In 2012, Doudna and Emmanuelle Charpentier were the first to propose that CRISPR-Cas9 (enzymes from bacteria that control microbial immunity) could be used for programmable editing of genomes,[10][11] which has been called one of the most significant discoveries in the history of biology.[12] Since then, Doudna has been a leading figure in what is referred to as the "CRISPR revolution" for her fundamental work and leadership in developing CRISPR-mediated genome editing.[10]

Dr Jennifer Doudna at the Innovative Genomics Institute

Her many other awards and fellowships include the 2000 Alan T. Waterman Award for her research on the structure of a ribozyme, as determined by X-ray crystallography[13] and the 2015 Breakthrough Prize in Life Sciences for CRISPR-Cas9 genome editing technology, with Charpentier.[14] She has been a co-recipient of the Gruber Prize in Genetics (2015),[15] the Tang Prize (2016),[16] the Canada Gairdner International Award (2016),[17] and the Japan Prize (2017).[18] She was named one of the Time 100 most influential people in 2015.[19]


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