Iodotyrosine
3-Iodotyrosine
Chemical compound
3-Iodotyrosine is an intermediate in the synthesis of thyroid hormones which is derived from iodination of tyrosine at the meta-position of the benzene ring. One unit can combine with diiodotyrosine to form triiodothyronine, as occurs in the colloid of the thyroid follicle. Two units can combine to form 3,3'-diiodothyronine.
3-Iodotyrosine is a reversible inhibitor of the enzyme tyrosine hydroxylase.[2]