Hexahydrocannabiphorol

Hexahydrocannabiphorol

Hexahydrocannabiphorol

Semi-sythetic cannabinoid drug

Hexahydrocannabiphorol (HHCP, sometimes mistakenly referred to as hexahydroxycannabiphorol) is a semi-synthetic cannabinoid derivative which has been marketed since around 2021.[1][2] It is believed to be made from the hydrogenation of tetrahydrocannabiphorol (THCP). THCP is only reported as a trace component of cannabis in 2019.[3] HHCP was studied by Roger Adams as early as 1942.[4]

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Legality

The legal status of hexahydrocannabinol and derivatives varies between countries, leading to widespread sale in some jurisdictions in Europe and the US.

In France, HHCP was banned in 2023.[5]

In Japan, Japanese Health Ministry announced that six synthetic cannabinoids with structures similar to HHCH, including HHCP, were to be banned from 6 January 2024.[6]

HHCP was banned in Slovakia as of 13 January 2024.[citation needed]

See also

References

  1. [1]
    Tanaka R, Kikura-Hanajiri R (June 2023). "Identification of hexahydrocannabinol (HHC), dihydro-iso-tetrahydrocannabinol (dihydro-iso-THC) and hexahydrocannabiphorol (HHCP) in electronic cigarette cartridge products". Forensic Toxicology. 42 (1): 71–81. doi:10.1007/s11419-023-00667-9. PMID 37365398. S2CID 259259903.
  2. [2]
    Höfert L, Becker S, Dreßler J, Baumann S (August 2023). "Quantification of (9R)- and (9S)-hexahydrocannabinol (HHC) via GC-MS in serum/plasma samples from drivers suspected of cannabis consumption and immunological detection of HHC and related substances in serum, urine, and saliva". Drug Testing and Analysis. 16 (5): 489–497. doi:10.1002/dta.3570. PMID 37652872. S2CID 261430819.
  3. [3]
    Hexahydrocannabinol (HHC) and related substances. European Monitoring Centre for Drugs and Drug Addiction, 2023
  4. [4]
    Adams, Roger; Loewe, S.; Smith, C. M.; McPhee, W. D. (1942). "Tetrahydrocannabinol Homologs and Analogs with Marihuana Activity. XIII1". Journal of the American Chemical Society. 64 (3): 694–697. doi:10.1021/ja01255a061.
  5. [5]
    "Actualité - L'ANSM classe l'hexahydrocannabinol (HHC) et deux de ses dérivés sur la liste des stupéfiants" [News - The ANSM classifies hexahydrocannabinol (HHC) and two of its derivatives on the list of narcotics]. Agence nationale de sécurité du médicament et des produits de santé (ANSM) (in French). Retrieved 2023-06-12.
  6. [6]
    https://english.kyodonews.net/news/2023/12/20893a7e69cb-japan-decides-to-ban-more-cannabinoids-after-gummies-sicken-people.doc
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