HES2

HES2
Identifiers
Aliases	HES2, bHLHb40, hes family bHLH transcription factor 2
External IDs	OMIM: 609970; MGI: 1098624; HomoloGene: 22455; GeneCards: HES2; OMA:HES2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	6,424,670 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	152,246,926 bp
RNA expression pattern
	Top expressed in
	placenta; ; skin of abdomen; ; vagina; ; right uterine tube; ; oral cavity; ; rectum; ; vulva; ; human penis; ; amniotic fluid; ; bronchial epithelial cell;
	Top expressed in
	lip; ; jejunum; ; proximal tubule; ; duodenum; ; yolk sac; ; esophagus; ; lens; ; colon; ; stomach; ; zone of skin;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; double-stranded DNA binding; transcription factor binding; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; transcription corepressor activity; sequence-specific DNA binding; sequence-specific double-stranded DNA binding;
Cellular component	nucleus;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; somitogenesis; Notch signaling pathway; cell differentiation; regulation of neurogenesis; anterior/posterior pattern specification;
	Sources:Amigo / QuickGO
Orthologs
	54626
	15206
	ENSG00000069812
	ENSMUSG00000028940
	Q9Y543
	O54792
	NM_019089
	NM_001301805; NM_008236
	NP_061962
	NP_001288734; NP_032262
	Wikidata
View/Edit Human	View/Edit Mouse

Hes family bhlh transcription factor 2

Protein-coding gene in the species Homo sapiens

Hes family bHLH transcription factor 2 is a protein that in humans is encoded by the HES2 gene.^[5]

Quick Facts HES2, Identifiers ...

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This article uses material from the Wikipedia article HES2, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000069812 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000028940 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] [5]
"Entrez Gene: Hes family bHLH transcription factor 2".

[5]

[1]

[2]

[3]

[4]

HES2

Hes family bhlh transcription factor 2

References

Further reading

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