Glutathione—cystine_transhydrogenase

Glutathione—cystine transhydrogenase

Glutathione—cystine transhydrogenase

Add article description

In enzymology, a glutathione—cystine transhydrogenase (EC 1.8.4.4) is an enzyme that catalyzes the chemical reaction

2 glutathione + cystine glutathione disulfide + 2 cysteine
Quick Facts Identifiers, EC no. ...

Thus, the two substrates of this enzyme are glutathione and cystine, whereas its two products are glutathione disulfide and cysteine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:cystine oxidoreductase. Other names in common use include GSH-cystine transhydrogenase, and NADPH-dependent GSH-cystine transhydrogenase. This enzyme participates in cysteine metabolism and glutathione metabolism.

References

    • Nagai S, Black S (1968). "A thiol-disulfide transhydrogenase from yeast". J. Biol. Chem. 243 (8): 1942–7. PMID 5646485.


    This EC 1.8 enzyme-related article is a stub. You can help Wikipedia by expanding it.
    Share this article:

    This article uses material from the Wikipedia article Glutathione—cystine_transhydrogenase, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.