Coronavirus._SARS-CoV-2.png
Contents
Summary
Description Coronavirus. SARS-CoV-2.png |
Deutsch:
Wissenschaftlich genaues Atommodell der äußeren Struktur des
SARS
Coronavirus 2 (
SARS-CoV-2
), einem
Stamm
(genetische Variante) des Coronavirus, der die Coronavirus-Krankheit (
COVID-19
) verursachte und erstmals im Dezember 2019 in
Wuhan
,
China
, identifiziert wurde.
Jeder einzelne Ort (amorpher Fleck) ist ein Atom von:
English:
Scientifically accurate atomic model of the external structure of the
Severe Acute Respiratory Syndrome
CoronaVirus 2
(SARS-CoV-2), a
strain
(
genetic variant
) of the
coronavirus
that caused
coronavirus disease
(COVID-19), first identified in
Wuhan
,
China
, during December 2019
Each separate locus (amorphous blob) is a molecule of:
Español:
Modelo atómico de la estructura externa del
SARS-CoV-2
. Cada "bola" es un
átomo
.
Русский:
Научно достоверная атомарная модель внешней структуры коронавируса (SARS-CoV-2). Каждый "шарик" — атом.
Опубликовано
на
N+1
.
Научный консультант:
Protein Data Bank: 2mls, 6y3y, 5x29, 6yyt Charmm-gui: 6vsb_1_1_1_S309
Проект был сделан в соответствии с научными источниками:
Первичные источники:
|
Date | |
Source |
Own work . Scientific consultants:
|
Author | Alexey Solodovnikov (Idea, Producer, CG, Editor), Valeria Arkhipova (Scientific Сonsultant) |
Permission
( Reusing this file ) |
Published by N+1 a popular science online publication of Russia ( https://nplus1.ru/ ), protein models are derivative works of the free license site (freely available for both non-commercial and commercial use) |
Other versions |
|
Sources
Primary sources:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489918/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098027/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605623/
The following structures from open sources were used in the work, Protein Data Bank ( https://www.rcsb.org ):
- 2mls ( membrane bilayer complex with matrix metalloproteinase -12 at its beta-face ) Koppisetti, R.K., Fulcher, Y.G., Prior, S.H., Lenoir, M., Overduin, M., Van Doren, S.R. 2014
- 6y3y ( human coronavirus HKU1 haemagglutinin-esterase ) Hurdiss, D.L., Drulyte, I., Pronker, M.F. 2020
- 5x29 ( NMR structure of the SARS Coronavirus E protein pentameric ion channel ) Torres, J., Surya, W., Li, Y. 2017
- 6yyt ( Structure of replicating SARS-CoV-2 polymerase ) Hillen, H.S., Kokic, G., Farnung, L., Dienemann, C., Tegunov, D., Cramer, P. 2020
- Charmm-gui : 6vsb_1_1_1_S309
Additional sources:
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- Koppisetti, R. K., Fulcher, Y. G., Jurkevich, A., Prior, S. H., Xu, J., Lenoir, M., Overduin, M., Van Doren, S. R. Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12 // Nat. Commun. – 2014. – Vol. 5. – P. 1–14.
- Hillen, H. S., Kokic, G., Farnung, L., Dienemann, C., Tegunov, D., Cramer, P. Structure of replicating SARS-CoV-2 polymerase // Nature. – 2020. – Vol. 584. – N. 7819. – P. 154–156.
- Harris, L. J., Larson, S. B., Hasel, K. W., McPherson, A. Refined structure of an intact IgG2a monoclonal antibody // Biochemistry. – 1997. – Vol. 36. – N. 7. – P. 1581–1597.
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- Yao, H., Song, Y., Chen, Y., Wu, N., Xu, J., Sun, C., Zhang, J., Weng, T., Zhang, Z., Wu, Z., Cheng, L., Shi, D., Lu, X., Lei, J., Crispin, M., Shi, Y., Li, L., Li, S. Molecular Architecture of the SARS-CoV-2 Virus // Cell. – 2020. – Vol. 183. – N. 3. – P. 730-738.e13.
- Oostra, M., de Haan, C. A. M., de Groot, R. J., Rottier, P. J. M. Glycosylation of the Severe Acute Respiratory Syndrome Coronavirus Triple-Spanning Membrane Proteins 3a and M // J. Virol. – 2006. – Vol. 80. – N. 5. – P. 2326–2336. ( https://europepmc.org/article/MED/16474139 )
- B.W. Neuman, M. J. B. Supramolecular Architecture of the Coronavirus Particle // Adv. Virus Res. – 2020. – Vol. 96. – P. 1–27 ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112365/ , https://europepmc.org/article/PMC/1563832 )
- Neuman, B. W., Kiss, G., Kunding, A. H., Bhella, D., Baksh, M. F., Connelly, S., Droese, B., Klaus, J. P., Makino, S., Sawicki, S. G., Siddell, S. G., Stamou, D. G., Wilson, I. A., Kuhn, P., Buchmeier, M. J. A structural analysis of M protein in coronavirus assembly and morphology // J. Struct. Biol. – 2011. – Vol. 174. – N. 1. – P. 11–22. ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486061/ )
- Yu, A., Pak, A. J., He, P., Monje-Galvan, V., Casalino, L., Gaieb, Z., Dommer, A. C., Amaro, R. E., Voth, G. A. A multiscale coarse-grained model of the SARS-CoV-2 virion // Biophys. J. – 2021. – Vol. 120. – N. 6. – P. 1097–1104 ( https://europepmc.org/article/PMC/PMC7695975 , https://search.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/covidwho-947143 )
- Yao, H., Song, Y., Chen, Y., Wu, N., Xu, J., Sun, C., Zhang, J., Weng, T., Zhang, Z., Wu, Z., Cheng, L., Shi, D., Lu, X., Lei, J., Crispin, M., Shi, Y., Li, L., Li, S. Molecular architecture of the SARS-CoV-2 virus // Cell. – 2020. – Vol. 183. – N. 3. – P. 730–738 ( https://www.sciencedirect.com/science/article/pii/S0092867420311594 )
- Choi, Y. K., Cao, Y., Frank, M., Woo, H., Park, S. J., Yeom, M. S., Croll, T. I., Seok, C., Im, W. Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane // J. Chem. Theory Comput. – 2021. – Vol. 17. – N. 4. – P. 2479–2487 ( https://www.researchgate.net/publication/349986293_Structure_Dynamics_Receptor_Binding_and_Antibody_Binding_of_the_Fully_Glycosylated_Full-Length_SARS-CoV-2_Spike_Protein_in_a_Viral_Membrane )
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Assessment
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