Ferredoxin—NAD+_reductase
In enzymology, a ferredoxin–NAD+ reductase (EC 1.18.1.3) is an enzyme that catalyzes the chemical reaction:
- reduced ferredoxin + NAD+ oxidized ferredoxin + NADH + H+
Thus, the two substrates of this enzyme are reduced ferredoxin and NAD+, whereas its 3 products are oxidized ferredoxin, NADH, and H+. This enzyme participates in fatty acid metabolism.
This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor.
The systematic name of this enzyme is ferredoxin:NAD+ oxidoreductase. There are a variety of names in common use:
- ferredoxin–nicotinamide adenine dinucleotide reductase
- ferredoxin reductase
- NAD+-ferredoxin reductase
- ferredoxin–NAD+ reductase
- ferredoxin–linked NAD+ reductase
- ferredoxin–NAD reductase
When NAD molecule is in its reduced form, the enzyme is referred to as:
- NADH-ferredoxin oxidoreductase
- reduced nicotinamide adenine dinucleotide-ferredoxin
- NADH-ferredoxin reductase
- NADH flavodoxin oxidoreductase
- NADH2-ferredoxin oxidoreductase
Other enzymes in the family include:
- NADH-ferredoxin NAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)
- NADH-ferredoxin TOL reductase (component of toluene dioxygenase)