Estrostep
Ethinylestradiol/norethisterone acetate
Pharmaceutical combination
Ethinylestradiol/norethisterone acetate (EE/NETA), or ethinylestradiol/norethindrone acetate, is a combination of ethinylestradiol (EE) and norethisterone acetate (NETA) which is used as birth control and menopausal hormone therapy.[1][2] EE is an estrogen, while norethisterone acetate (NETA) is a progestin.[1] It is taken by mouth.[1] Some preparations of EE/NETA used in birth control additionally contain an iron supplement in the form of ferrous fumarate.[3]
In 2021, it was the 52nd most commonly prescribed medication in the United States, with more than 12 million prescriptions.[4][5] It is available as a generic medication.[6]
In addition, branded formulations of this hormone combination when used for birth control are only available by prescription in the US.