Endoneuraminidase

Endo-alpha-sialidase

Endo-alpha-sialidase

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Endo-α-sialidase (EC 3.2.1.129, endo-N-acylneuraminidase, endoneuraminidase, endo-N-acetylneuraminidase, poly(α-2,8-sialosyl) endo-N-acetylneuraminidase, poly(α-2,8-sialoside) α-2,8-sialosylhydrolase, endosialidase, endo-N) is an enzyme with systematic name polysialoside (2→8)-α-sialosylhydrolase.[1][2][3][4][5][6][7] It catalyses the following chemical reaction:

Endohydrolysis of (2→8)-α-sialosyl linkages in oligo- or poly(sialic) acids

References

  1. Finne J, Mäkelä PH (January 1985). "Cleavage of the polysialosyl units of brain glycoproteins by a bacteriophage endosialidase. Involvement of a long oligosaccharide segment in molecular interactions of polysialic acid". The Journal of Biological Chemistry. 260 (2): 1265–70. doi:10.1016/S0021-9258(20)71238-X. PMID 3968060.
  2. Hallenbeck PC, Vimr ER, Yu F, Bassler B, Troy FA (March 1987). "Purification and properties of a bacteriophage-induced endo-N-acetylneuraminidase specific for poly-α-2,8-sialosyl carbohydrate units". The Journal of Biological Chemistry. 262 (8): 3553–61. doi:10.1016/S0021-9258(18)61387-0. PMID 3546309.
  3. Kwiatkowski B, Boschek B, Thiele H, Stirm S (August 1982). "Endo-N-acetylneuraminidase associated with bacteriophage particles". Journal of Virology. 43 (2): 697–704. doi:10.1128/JVI.43.2.697-704.1982. PMC 256172. PMID 7109038.



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