Afua (/ˈæfwə/, AF-wə) or Efua (/ˈɛfwə/, EF-wə) is an Akan day name traditionally given to girls born on a Friday; the equivalent male name is Kofi.

• Afua Adwo Jectey Hesse, Ghanaian pædiatric surgeon and former president of the Medical Women's International Association
• Afua Bruce, American engineer, data executive, professor, and politician
• Afua Cooper (born 1957), Canadian historian and dub poet, born in Jamaica
• Afua Hirsch (born 1981), British writer, broadcaster, and former barrister, born in Norway
• Afua Kobi (fl. 1834–1884), asantehemaa of the Ashanti Empire
• Afua Kuma (1908–1987), Ghanaian oral theologian
• Afua Osei, American entrepreneur and public speaker, co-founder of She Leads Africa
• Afua Richardson (born 1980), African–Native American comic book artist
• Efua Asibon, Ghanaian businesswoman
• Efua Baker (born c. 1967), British singer-songwriter and celebrity fitness expert, born in Ghana
• Efua Dorkenoo (1949–2014), affectionately known as "Mama Efua", Ghanaian-British campaigner against female genital mutilation
• Efua Sutherland (1924–1996), Ghanaian playwright, director, dramatist, children's author, poet, educationalist, researcher, child advocate, and cultural activist
• Efua Traoré, Nigerian-German writer

• Afuʻalo Matoto, Tongan political figure and life peer
• Afuang: Bounty Hunter, 1988 Philippine biographical action film
• Charles Afuakwah (born 1966), Scottish former rugby union player born in Ghana

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