Dibenzothiophene_dihydrodiol_dehydrogenase

Dibenzothiophene dihydrodiol dehydrogenase

Dibenzothiophene dihydrodiol dehydrogenase

Class of enzymes

In enzymology, a dibenzothiophene dihydrodiol dehydrogenase (EC 1.3.1.60) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+ 1,2-dihydroxydibenzothiophene + NADH + H+
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Thus, the two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and NAD+, whereas its 3 products are 1,2-dihydroxydibenzothiophene, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase.

References

    • Laborde AL, Gibson DT (1977). "Metabolism of dibenzothiophene by a Beijerinckia species". Appl. Environ. Microbiol. 34 (6): 783–90. PMC 242748. PMID 596875.
    • Denome SA, Stanley DC, Olson ES, Young KD (1993). "Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway". J. Bacteriol. 175 (21): 6890–901. PMC 206814. PMID 8226631.


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