Franklin D. Roosevelt, the 32nd President of the United States, has inspired or been portrayed in numerous cultural works.

• The Golden Age, a 2000 novel by Gore Vidal
• Southern Victory series by Harry Turtledove
• The War That Came Early series by Harry Turtledove
• Worldwar series by Harry Turtledove
• Joe Steele by Harry Turtledove
• Days of Infamy series by Harry Turtledove
• Or Even Eagle Flew by Harry Turtledove
• The Plot Against America (2004) novel by Philip Roth
• Axis of Time series by John Birmingham
• The Proteus Operation by James P. Hogan
• Hitler's Peace by Philip Kerr
• The Man in the High Castle by Philip K. Dick
• SS-GB by Len Deighton
• 1945 by Newt Gingrich and William R. Forstchen
• The Shape of Things to Come by H.G. Wells

• Yankee Doodle Dandy, a 1942 film
• This is the Army, a 1943 film
• Mission to Moscow, a 1943 film
• The Beginning or the End, a 1947 docudrama
• Beau James, a 1957 film
• Sunrise at Campobello, a 1960 film based on the play of the same name
• The Private Files of J. Edgar Hoover, a 1977 film
• Annie, a 1982 adaptation of the musical of the same name
• Pearl Harbor, a 2001 film
• FDR: American Badass!, a 2012 film
• Hyde Park on Hudson, a 2012 film
• The Monuments Men, a 2014 film
• Darkest Hour, a 2017 film
• Justice Society: World War II, a 2021 film

• Eleanor and Franklin, a 1976 television miniseries
• Eleanor and Franklin: The White House Years, a 1977 television film
• The Winds of War, a 1983 miniseries^[1]
• War and Remembrance, a 1989 miniseries and sequel to The Winds of War
• The Kennedys of Massachusetts, a 1990 television film
• World War II: When Lions Roared, 1994 biographical miniseries
• Truman, a 1995 television film
• Winchell, a 1998 television film
• Annie, a 1999 television movie adaptation of the musical of the same name
• Warm Springs, a 2005 television film
• Into the Storm, a 2009 television film
• All the Presidents' Heads, a 2011 episode of the television series Futurama
• The World Wars, a 2014 documentary miniseries
• The Roosevelts, a 2014 documentary film depicting the Roosevelt family
• Atlantic Crossing, 2020 television series^[2]
• The New Deal (Agents of S.H.I.E.L.D.), a 2020 episode of the television series Agents of S.H.I.E.L.D.
• The First Lady, a 2022 television series.
• Konpeki no Kantai a 1990-1996 animated television series.

• Annie, a 1976 musical
• I'd Rather Be Right, a 1937 musical
• Sunrise at Campobello, a 1958 play

• Civilization, a series of turn-based strategy games
• Hearts of Iron, a series of grand strategy games depicting World War II
• The Political Machine, a series of presidential campaign simulation games

• Ace Kilroy, a webcomic

• Presidential $1 Coin Program
• Roosevelt dime

• List of memorials to Franklin D. Roosevelt

He is the subject of the song, "Papa Roosevelt," a song in Spanish by the Puerto Rican group, Los Jardineros, which can be found on YouTube.