Charles Dougherty may refer to:

• Charles Dougherty (Georgia politician) (1801–1853), American politician from Georgia, Whig candidate for Governor of Georgia
• Charles F. Dougherty (born 1937), U.S. Representative from Pennsylvania
• Charles J. Dougherty (born 1949), President of Duquesne University in Pittsburgh, Pennsylvania
• Charles Dougherty (Florida politician) (1850–1915), Democrat U.S. Representative from Florida
• Charlie Dougherty (1862–1925), baseball player
• Charles Dougherty (baseball) (1879–1939), American baseball player in the pre-Negro leagues
• Charles B. Dougherty (1860–1924), officer in the Pennsylvania Army National Guard

• Charles Doherty (1855–1931), Canadian politician and jurist
• Charles Doughty (disambiguation)

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