AP-1_site

AP-1 binding site

AP-1 binding site

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The AP-1 binding site, also known as the AP-1 promoter site, is a DNA sequence to which AP-1 transcription factors are able to bind.[1] The AP-1 binding site, in humans, has a nucleotide sequence of ATGAGTCAT, where A corresponds to adenine, T corresponds to thymine, G corresponds to guanine, and C corresponds to cytosine.


References

  1. Kim, H; Pennie, W D; Sun, Y; Colburn, N H (1 June 1997). "Differential functional significance of AP-1 binding sites in the promoter of the gene encoding mouse tissue inhibitor of metalloproteinases-3". Biochemical Journal. 324 (2): 547–553. doi:10.1042/bj3240547. PMC 1218465. PMID 9182717.



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