A-santonin_1,2-reductase

Alpha-santonin 1,2-reductase

Alpha-santonin 1,2-reductase

Class of enzymes

In enzymology, an alpha-santonin 1,2-reductase (EC 1.3.1.47) is an enzyme that catalyzes the chemical reaction

1,2-dihydrosantonin + NAD(P)+ alpha-santonin + NAD(P)H + H+
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The 3 substrates of this enzyme are 1,2-dihydrosantonin, NAD+, and NADP+, whereas its 4 products are alpha-santonin, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase.

References

    • Naik U, Mavuinkurve S (1987). "alpha-Santonin 1,2-reductase and its role in the formation of dihydrosantonin and lumisantonin by Pseudomonas cichorii S". Can. J. Microbiol. 33 (8): 658–62. doi:10.1139/m87-115. PMID 3690421.


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