8-hydroxy-5-deazaflavin:NADPH_oxidoreductase

8-Hydroxy-5-deazaflavin:NADPH oxidoreductase

8-Hydroxy-5-deazaflavin:NADPH oxidoreductase

Class of enzymes

8-Hydroxy-5-deazaflavin:NADPH oxidoreductase (EC 1.5.1.40, 8-OH-5dFl:NADPH oxidoreductase) is an enzyme with systematic name reduced coenzyme F420:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

reduced coenzyme F420 + NADP+ coenzyme F420 + NADPH + H+
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The enzyme requires the 5-deazaflavin structure, as well as an 8-hydroxy group in the substrate.

References

  1. [1]
    Eker AP, Hessels JK, Meerwaldt R (January 1989). "Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus". Biochimica et Biophysica Acta (BBA) - General Subjects. 990 (1): 80–6. doi:10.1016/s0304-4165(89)80015-7. PMID 2492438.
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