The 50th Anniversary Saturn Awards, presented by the Academy of Science Fiction, Fantasy and Horror Films and honoring the best in science fiction, fantasy, horror, and other genres belonging to genre fiction in film, television, and home entertainment, were held on October 25, 2022, at Los Angeles Marriott Burbank Airport Hotel in Burbank, California, and live-streamed on Electric Entertainment's OTT app and FAST channel ElectricNow.^{[1][2][3][4][5]} The nominations were announced on August 12, 2022.^[6][7][8][9] Actor and comedian Joel McHale hosted the event.^[10]

The 50th Saturn awards were preceded by the 46th Saturn Awards, held in 2021. The decision to rebrand what would have been the "47th Saturn Awards" to the "50th Saturn Awards", was made in order to celebrate 50 years of the Saturn Awards, which were founded in 1972.^[11]

This year, several new television categories were introduced. For the first time since the 45th Saturn Awards, the television awards were split into "Network / Cable" and "Streaming" categories; however, this was discontinued the following ceremony. Disney+ received the most nominations with 26 for "Streaming", followed by Netflix with 17; AMC dominated the nominations for "Network / Cable" with 17.^[6][12][13]

The Batman led the nominations for film with twelve, including Best Superhero Film and four acting nominations, followed by Nightmare Alley with ten and Spider-Man: No Way Home with nine.^[6] For television, Better Call Saul (AMC) led the nominations for "Network / Cable" with seven, followed by Superman & Lois (The CW) and The Walking Dead (AMC) with six each.^[6][14][15] Severance (Apple TV+) and Stranger Things (Netflix) led the nominations for the "Streaming" television categories with six each, followed by Obi-Wan Kenobi (Disney+) with five mentions.^[6]