4,4'-diapophytoene_desaturase

4,4'-Diapophytoene desaturase

4,4'-Diapophytoene desaturase

Enzyme

4,4'-Diapophytoene desaturase (EC 1.3.8.2, dehydrosqualene desaturase, CrtN, 4,4'-diapophytoene:FAD oxidoreductase) is an enzyme with systematic name 15-cis-4,4'-diapophytoene:FAD oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

15-cis-4,4'-diapophytoene + 4 FAD all-trans-4,4'-diapolycopene + 4 FADH2 (overall reaction)
(1a) 15-cis-4,4'-diapophytoene + FAD all-trans-4,4'-diapophytofluene + FADH2
(1b) all-trans-4,4'-diapophytofluene + FAD all-trans-4,4'-diapo-zeta-carotene + FADH2
(1c) all-trans-4,4'-diapo-zeta-carotene + FAD all-trans-4,4'-diaponeurosporene + FADH2
(1d) all-trans-4,4'-diaponeurosporene + FAD all-trans-4,4'-diapolycopene + FADH2
Quick Facts Identifiers, EC no. ...

This enzyme is typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.

References

  1. [1]
    Wieland B, Feil C, Gloria-Maercker E, Thumm G, Lechner M, Bravo JM, Poralla K, Götz F (December 1994). "Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus". Journal of Bacteriology. 176 (24): 7719–26. doi:10.1128/JB.176.24.7719-7726.1994. PMC 197231. PMID 8002598.
  2. [2]
    Raisig A, Sandmann G (October 1999). "4,4'-diapophytoene desaturase: catalytic properties of an enzyme from the C30 carotenoid pathway of Staphylococcus aureus". Journal of Bacteriology. 181 (19): 6184–7. doi:10.1128/JB.181.19.6184-6187.1999. PMC 103650. PMID 10498735.
  3. [3]
    Raisig A, Sandmann G (September 2001). "Functional properties of diapophytoene and related desaturases of C30 and C40 carotenoid biosynthetic pathways". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1533 (2): 164–70. doi:10.1016/s1388-1981(01)00154-8. PMID 11566453.
Share this article:

This article uses material from the Wikipedia article 4,4'-diapophytoene_desaturase, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.