3,4-dehydroadipyl-CoA_semialdehyde_dehydrogenase_(NADP+)

3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)

3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)

Class of enzymes

3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) (EC 1.2.1.77, BoxD, 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase) is an enzyme with systematic name 3,4-didehydroadipyl-CoA semialdehyde:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

3,4-didehydroadipyl-CoA semialdehyde + NADP+ + H2O 3,4-didehydroadipyl-CoA + NADPH + H+
Quick Facts +), Identifiers ...

This enzyme catalyses a step in the aerobic benzoyl-coenzyme A catabolic pathway in Azoarcus evansii and Burkholderia xenovorans.

References

  1. [1]
    Gescher J, Ismail W, Olgeschläger E, Eisenreich W, Wörth J, Fuchs G (April 2006). "Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase". Journal of Bacteriology. 188 (8): 2919–27. doi:10.1128/JB.188.8.2919-2927.2006. PMC 1446997. PMID 16585753.
  2. [2]
    Bains J, Boulanger MJ (June 2008). "Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400". Journal of Molecular Biology. 379 (3): 597–608. doi:10.1016/j.jmb.2008.04.031. PMID 18462753.
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