The 2021 EchoPark Texas Grand Prix was a NASCAR Cup Series race that was held on May 23, 2021, at Circuit of the Americas in Austin, Texas. Originally scheduled for 68 laps on the 3.426-mile (5.514 km) road course, the race was shortened to 54 laps by heavy rain. It was the 14th race of the 2021 NASCAR Cup Series season.

In a wet practice session, William Byron was the fastest in the practice session with a time of 2:37.694 with an average speed of 77.847 mph (125.283 km/h).^[11]

In a dry track, Tyler Reddick scored the pole for the race with a time of 2:12.911 and a speed of 92.363 mph (148.644 km/h).^[12]

NASCAR also implemented a new rule for qualifying. For road course qualifying, a timing loop marked on the circuit, not the start-finish line, will set official time. The rule is similar to that used by INDYCAR, which also uses knockout qualifying. At this circuit, the exit of Istanbul 8 will be used as the timing line.

Tyler Reddick won his first career pole in qualifying. It began to rain on the first lap and all drivers pitted to change from slick tires to treaded rain tires. Kevin Harvick got heavy damage after making contact with Ryan Blaney, which also collected Christopher Bell and Bubba Wallace. Joey Logano won the first stage. In the second stage, the rain picked up, and the ensuing spray created visibility issues. In one incident, Martin Truex Jr. got into the back of Michael McDowell and then was rammed into by Cole Custer, severely damaging both cars, and causing Custer's car to catch on fire. Kyle Busch won the second stage. On a round of green flag pit stops, Kyle Larson passed Busch for the lead. Alex Bowman took the lead from Larson and was then passed by Chase Elliott. The race was red flagged again due to heavier rain and was called official with 14 laps to go. Elliott was awarded the win, giving Chevrolet its 800th win in NASCAR and Hendrick Motorsports its 268th win, tying Petty Enterprises for the most wins by team in NASCAR history.