2-Deoxy-scyllo-inosamine_dehydrogenase

2-Deoxy-scyllo-inosamine dehydrogenase

2-Deoxy-scyllo-inosamine dehydrogenase

Class of enzymes

2-deoxy-scyllo-inosamine dehydrogenase (EC 1.1.1.329, neoA (gene name), kanK (gene name)) is an enzyme with systematic name 2-deoxy-scyllo-inosamine:NAD(P)+ 1-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

2-deoxy-scyllo-inosamine + NAD(P)+ 3-amino-2,3-dideoxy-scyllo-inosose + NAD(P)H + H+
Quick Facts Identifiers, EC no. ...

This enzyme requires zinc.

References

  1. [1]
    Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K (December 2005). "Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773". The Journal of Antibiotics. 58 (12): 766–74. doi:10.1038/ja.2005.104. PMID 16506694.
  2. [2]
    Nepal KK, Oh TJ, Sohng JK (May 2009). "Heterologous production of paromamine in Streptomyces lividans TK24 using kanamycin biosynthetic genes from Streptomyces kanamyceticus ATCC12853". Molecules and Cells. 27 (5): 601–8. doi:10.1007/s10059-009-0080-5. PMID 19466609.
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