2-Butyl-3-(p-tolyl)quinuclidine

Butyltolylquinuclidine

Butyltolylquinuclidine

Stimulant drug


2-Butyl-3-(p-tolyl)quinuclidine (BTQ) is a stimulant DRI.[1] It is one of a number of substituted quinuclidine derivatives developed as potential medications for the treatment of cocaine abuse,[2] and produces similar effects to cocaine in animal studies, although milder and longer-lasting.

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References

  1. Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, et al. (March 2003). "2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors". Bioorganic & Medicinal Chemistry. 11 (6): 1123–36. doi:10.1016/S0968-0896(02)00450-9. PMID 12614900.
  2. Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S (February 2003). "Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors". Bioorganic & Medicinal Chemistry Letters. 13 (3): 513–7. doi:10.1016/S0960-894X(02)00943-5. PMID 12565962.

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