The 1959 Copa Chile was the second edition of the Chilean Cup tournament. The competition started on November 21, 1959, and concluded on December 22, 1959. Santiago Wanderers won the competition for the first time, beating Deportes La Serena on the final.

Matches were scheduled to be played at the stadium of the team named first on the date specified for each round. From the beginning of the second Round, if scores were level after 90 minutes had been played, an extra time took place.

• José Sulantay (Deportes La Serena) 6 goals
• Juan Soto (Colo-Colo) 6 goals
• Héctor Torres (Magallanes) 6 goals

• 1959 Campeonato Nacional
• Primera B

• Revista Estadio (Santiago, Chile) November, December 1959 (revised scores & information)
• RSSSF (secondary source, some mistakes in it)