1,2-dehydroreticulinium_reductase_(NADPH)

1,2-dehydroreticulinium reductase (NADPH)

1,2-dehydroreticulinium reductase (NADPH)

Class of enzymes

In enzymology, a 1,2-dehydroreticulinium reductase (NADPH) (EC 1.5.1.27) is an enzyme that catalyzes the chemical reaction

(R)-reticuline + NADP+ 1,2-dehydroreticulinium + NADPH + H+
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Thus, the two substrates of this enzyme are (R)-reticuline and NADP+, whereas its 3 products are 1,2-dehydroreticulinium, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-reticuline:NADP+ oxidoreductase. This enzyme is also called 1,2-dehydroreticulinium ion reductase. This enzyme participates in alkaloid biosynthesis i.

References

    • De-Eknamkul W, Zenk MH (1992). "Purification and properties of 1,2-dehydroreticulinium reductase from Papaver somniferum seedlings". Phytochemistry. 31 (3): 813–821. doi:10.1016/0031-9422(92)80020-F.
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