(+)-pulegone_reductase

(+)-Pulegone reductase

(+)-Pulegone reductase

Class of enzymes


(+)-pulegone reductase (EC 1.3.1.81) is an enzyme with systematic name (−)-menthone:NADP+ oxidoreductase.[1] This enzyme catalises the following chemical reaction

(1) (−)-menthone + NADP+ (+)-pulegone + NADPH + H+
(2) (+)-isomenthone + NADP+ (+)-pulegone + NADPH + H+

NADH cannot replace NADPH as reductant.


References

  1. Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R (October 2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics. 418 (1): 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086.

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