In enzymology, a (+)-neomenthol dehydrogenase (EC 1.1.1.208) is an enzyme that catalyzes the chemical reaction

(+)-neomenthol + NADP⁺ ${\displaystyle \rightleftharpoons }$ (−)-menthone + NADPH + H⁺

Thus, the two substrates of this enzyme are (+)-neomenthol and NADP⁺, whereas its 3 products are (−)-menthone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (+)-neomenthol:NADP⁺ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.