(+)-larreatricin_hydroxylase

(+)-Larreatricin hydroxylase

(+)-Larreatricin hydroxylase

Class of enzymes


(+)-Larreatricin hydroxylase (EC 1.14.99.47) is an enzyme with systematic name (+)-larreatricin:oxygen 3'-hydroxylase.[1] This enzyme catalyses the following chemical reaction

(+)-larreatricin + O2 + AH2 (+)-3'-hydroxylarreatricin + A + H2O

This enzyme is isolated from the plant Larrea tridentata (creosote bush) and can be produced recombinantly.[2]


References

  1. Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG (September 2003). "(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)". Proceedings of the National Academy of Sciences of the United States of America. 100 (19): 10641–6. Bibcode:2003PNAS..10010641C. doi:10.1073/pnas.1934562100. PMC 196857. PMID 12960376.
  2. Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, et al. (October 2018). "Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin". Chemistry: A European Journal. 24 (59): 15756–15760. doi:10.1002/chem.201803785. PMC 6220842. PMID 30113748.

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